4. USC vs Notre Dame 
Series Record: Notre Dame leads 42-31-5   
Trophy: The Jeweled Shillelagh 
The winner of this game has gone on to win the national title 19 times, plus these two schools have produced 11 Heisman winners. 
 
5. Army vs Navy 
Series Record: Series tied 49-50-7  
Award: Gold cloth stars to put on their letter sweaters for victories 
Notes: This game probably has more history and tradition than any other rivalry in the country. This game is also part of the Commander-In-Chief trophy(Army, Navy, & Air Force)   
 
6. Lafayette vs Lehigh 
Series Record: Lafayette leads 73-62-5   
Known as: " The Game"  
This is the most-played rivalry in college football history.

 
 
7. Florida State vs Miami 
Series Record: Miami leads 29-21 
Since the 1987, Florida State has lost out on playing for the national championship five times because of losses to Miami. The two teams have met 13 times in the last 18 years when both were ranked in the top ten. Since 1983, these two teams have combined for more national titles  than any other two rivals in the country. 
 
 
8. Texas vs Texas A&M 
Series Record: Texas leads the series, 70-34-5.  
This was voted the top college football rivalry in a USA Today online poll.  
 
9. Florida vs Georgia 
Series Record: Georgia leads the series, 45-35-2. 
Known as:  " World's Largest Outdoor Cocktail Party"  
Georgia may hold the series lead, but Florida has had Georgia's number since 1992. This rivalry is one of only a few that is played on a neutral site, Jacksonville, FL. 
 
10.  Nebraska vs Oklahoma 
Oklahoma leads the series, 41-37-3.  
The 1971 game was considered by many, the greatest college football game of all-time. 19 times during this series, one of these two teams have been rated #1. 
 
 

11. Harvard vs Yale  
Series Record: Yale leads 64-49-8  
Known as: " The Game"  
This game is the third most-played in history; only Layafette-Lehigh and Princeton-Yale have been played more often.

 
 
12. Auburn vs Georgia 
Series Record: Auburn leads 52-48-8  
" The Oldest Rivalry in the Deep South" . Like many other games, these two even argue about the overall record between the two teams. The schools played the first SEC overtime game in 1996. Both teams played their first College Football game against each other in 1892 in Atlanta, which Auburn won 10-0. 
 
13. USC vs UCLA 
Series Record: USC leads the series, 38-27-7  
Known as: The battle for the Victory Bell 
The winning team paints the bell in their color to match the gold: blue for UCLA, cardinal for USC. 
 
14. California vs Stanford 
Stanford leads the series, 54-40-11.  
Known as:  " The Big Game"  
The rivalry has a history of tight scoring games, with 50 having been decided by 7 points or less.   
 
15. Minnesota vs Wisconsin 
Series Record: Minnesota leads 59-48-8  
Trophy: Paul Bunyan's Axe 
This is the oldest rivalry in NCAA Division I-A. The teams have met every year since 1907. Before Paul Bunyan's Axe, the teams played for the " Slab of Bacon" , a piece of wood with the word " BACON" . The idea was that the winning team " brought home the bacon" .  
 
16. Ithaca College Vs. Suny Cortland 
Series Record: Series Ithaca leads 36-25-3 
Known as: Cortaca Jug 
Trophy: Jug 
Notes: The Cortaca Jug is the the annual College football game played between the Red Dragons of the State University of New York at Cortland and the Bombers of Ithaca College. The matchup is one of the most prominent in Division III football. The winner charges the field and it usually ends in fisticuffs or possible attempts at tearing down Cortland's goal post. Not Ryan and Justin in 2000.  

 
17. Florida vs Florida State 
Series Record: Florida leads 28-19-2   
In the 1990's, these programs were two of the best in the country. 
 
18. Alabama vs Tennessee 
Series Record: Alabama leads 43-37-7   
Trophy: The winning team gets victory cigars 
The victory cigar tradition for Alabama was started in the Bear Bryant era; Tennessee took up the tradition for themselves in the 1990's. 
 
19. Virginia vs Virginia Tech 
Series Record: Virginia Tech leads 44-37-5 
Trophy: The Commonwealth Cup 
 
20. Washington vs Washington State 
Series Record: Washington leads 63-28-6   
Trophy: The Apple Cup 
 
21. Arizona vs Arizona State 
Series Record: Arizona leads 44-33-1  
Trophy: The Territorial Championship Cup 
Known as " The Big Game" . The Territorial Cup is the oldest prize given as part of a rivalry series. First given in 1899, the cup had been missing for fifty years until being recently discovered.  
 
22. West Virginia vs Pitt 
Series Record: Pitt leads 59-36-3 
Trophy: The Backyard Brawl 
Known As: The rivalry is the 14th oldest college rivalry in the United States. There is some serious hate associated with this game.

23. Indiana vs Purdue 
Series Record: Purdue leads 66-35-6   
Trophy: The Old Oaken Bucket 
 
24. Georgia vs Georgia Tech 
Series Record: Georgia leads 56-38-5   
Known as: " Clean, Old-fashioned Hate"  
 

25. Clemson vs South Carolina 
Series Record: Clemson leads 62-36-4   
Known as: " Battle of the Palmetto State"